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Maintain a consistent sleep schedule

compared twice-daily oral administrations of 75 mg pregabalin alone ( n = 15) to an arm additionally treated with oral doses of 100 mg alpha lipoic acid (ALA) and 750 g methylcobalamin ( n = 15) over a period of 12 weeks

Aim for adequate water intake throughout the day, with particular attention to morning hydration before fasting injection

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Increases SIRT-1 activity as a result of enhanced NAD+ salvage, leading to beneficial epigenetic and metabolic reprogramming, including increased oxidative phosphorylation (OXPHOS) and muscle stem cell activation 1-3