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They found that genetic knockdown of USP30 increased CNS mitophagy, protected against dopaminergic neuron loss, and reduced -synuclein aggregation

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Earlier work demonstrated that BM cells from MM aspirates express CD38, CD203a, CD73, and CD26, with malignant plasma cells characterized by high CD38 expression and variable CD203a positivity, whereas CD73 is largely restricted to stromal and osteogenic cells (45)

If the protocol is not delivering, the clinic catches that early instead of three cycles later

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