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S.LiuW.HaoS

Endogenous hydrogen sulfide regulates xCT stability through persulfidation of OTUB1 at cysteine 91 in colon cancer cells

A.WhitwellJ

Oxid Med Cell Longev 2013, 972913, 10.1155/2013/972913 (2013)

Excessive burden of ROS, failure of clearance mechanisms and even lack of antioxidants may lead to the accumulation of ROS and to oxidative stress [40], which are associated with genetic damage and breast cancer onset [61,62,63,64,65]

Its mechanism involves promoting the accumulation of copper within cells, thereby triggering a cascade of lethal responses
