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Supplementary material The Supplementary Material for this article can be found online at: References 1 Alvarez-FernandezA.PawarN.Sanchez-PugaP.ZaccaiN

Crit Rev Food Sci Nutr 58(1):136 Garg M, Goyal A, Kumari S (2021) An update on the recent advances in cubosome: a novel drug delivery system

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In fact, this arrangement not only provides mechanical support but also regulates biochemical signaling pathways that are fundamental for the ECMs role in supporting cellular functions and thus maintaining tissue integrity