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EGFR can induce signaling pathways, including the PI3K/AKT/mammalian target of rapamycin (mTOR) pathway, RAS/RAF/MEK/ERK pathway, and JAK/STAT pathway, which are involved in the pathogenesis of various tumors, including NSCLC [21]

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Most adverse effects were mild to moderate in severity, with no treatment discontinuations directly attributed to curcumin use
