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APAP overdose is the most common cause of acute liver failure in the US, with around 30,000 patients admitted to hospitals every year, accounting for about 48% of acute liver failure diagnoses [7,8]

D-series resolvins, tested in male CD1 mice, were shown to attenuate mechanical allodynia in chemotherapy-induced peripheral neuropathy and formalin-induced inflammatory pain models (Luo et al., 2019b)

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These results confirm that the pheomelanin but not eumelanin model has redox-activity in the potential range bracketed by the E s of Ir 3+ and Fc (+0.25 V +0.55 V)