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TNF-mediated necroptosis in brain endothelial cells as a potential mechanism of increased seizure susceptibility in mice following systemic inflammation

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63,156 This observation holds significance in the context of diseases that frequently manifest in the forebrain, such as glioblastoma, suggesting the potential effectiveness of intranasal administration for therapeutic intervention

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doi:10.1056/NEJMra1615439 Edmonds M, Lzaro-Martnez JL, Alfayate-Garca JM, et al

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