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It has an hepatic metabolism, mainly because of the glucuro-conjugation of the molecule, with the formation of inactive metabolites
Thus, this might be recognized as a special heart-brain-blood vessels interacting axis (providing in the counteracted multiorgan failure, the attenuated myocardial lesions, and arrhythmias as an achieved important tool, either as a cause or as a consequence), peripheral and central interplay, as an essential defensive response [19,22,23,24,27,28,29,31,37,38,39,40]

however, in about 30% of cases, long-term problems such as facial weakness, involuntary facial movements, or persistent secretion of tears may arise

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These benefits translate to earlier return to normal activities, reduced rehabilitation duration, and better long-term surgical results

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