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Description
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When caloric restriction is present, mammals synthesise less IGF-1 and its synthesis in the liver is refractory to GH stimulation [128130]
As a synthetic fragment of human GH residues 176-191, it allows researchers to study the metabolic arm of GH signalling independently of IGF-1 pathway activation
Therapeutic potential of targeting cathepsin S in pulmonary fibrosis
1 2 The American Journal of Clinical Nutrition
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