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ASA can not only reduce drug resistance by blocking G0/G1 phase-resistant cells but also by inhibiting the phosphorylation of AKT ( In addition, NF-B has been proven to be related to the resistance of tamoxifen

Kim YG, Han K, Jeong JH, et al

GV-971, a sodium oligomannate, modulates gut microbiota amino acid metabolism to reduce the activation of T helper 1 cells, thereby inhibiting M1-type microglia activation, ultimately alleviating neuroinflammation and enhancing cognitive function in AD mice (165)

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Adding multiple additional compounds creates complexity that makes it impossible to identify what is working (or causing problems)