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It will also summarize current strategies to enhance MSC adaptability, survival rate, and functional expression, including genetic regulation, biomaterial-assisted transplantation, and microenvironment modulation, to provide a theoretical basis and feasible path for promoting the clinical translation of stem cell therapy in intervertebral disc regeneration

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Possible temporary reactions include: Mild soreness at the injection site Nausea, headache or dizziness for a day or two Occasional minor bruising Serious side effects are very rare