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Muscle pumps in the gym feel permanently fuller rather than transient

Here is a revised and more accurate explanation of the reasons a UK GP surgery might refuse to give a B12 injection a day earlier than scheduled, incorporating the points youve raised and providing a more scientifically grounded perspective: 1

doi: 10.1038/nm1786

You should not apply any cosmetics to the treated area within a 12-hour period

However, taking a very high dose can be dangerous and cause side effects

There's no stopwatch on when things will go back to normal, but it's commonly a matter of a few days to a week, depending on several factors