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Interfering with B12 Absorption Research shows metformin can block B12 absorption

Use copper peptides topical at 1 to 3%, pH 5.0 to 6.0

Lack of long-term safety data: Most peptides have not been tested in large-scale human studies

Unlike CJC-1295 with DAC, this version lacks the Drug Affinity Complex modification, resulting in a shorter half-life and more physiologic, pulse-like GH secretion patterns in vitro

Specific FAX approval authority is delegated to command/site ISSMs who may approve unclassified and secure FAX machines within a SCIF

Key Dates Include: Pre-release: April 2, 2025 Open for proposal submissions: April 23, 2025 DSIP Topic Q&A Closure: May 7, 2025, at 10:00 AM MT Close for proposal submissions: May 21, 2025, at 10:00 AM MT Participating DoD Components: Department of the Navy (Navy) Defense Health Agency (DHA) Defense Threat Reduction Agency (DTRA) Office of the Secretary of Defense (OSD) National Geospatial-Intelligence Agency (NGA) For further details on active topics and the submission process, you can explore the DoDs SBIR/STTR portal here