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This study underlined the importance of diet composition, not only the ratio between fat and other nutrients

During this process, excess iron could induce the excessive accumulation of ROS, which leads to oxidative stress and damages mitochondrial function in preimplantation mouse embryos

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10.1002/bit.23111

Organic Acid Testing is used in functional medicine to explore underlying biochemical patterns, including mitochondrial dysfunction, which Rossignol and Frye (2012) linked to neurocognitive presentations, that may help explain persistent symptoms, particularly in people experiencing ongoing fatigue

Aug 1993;105(2):572-578