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Heres the kicker: when the body gets more than needed, it tries to excrete the excess

Zechner, R., Madeo, F

However, corticosteroids have significant limitations: Short-Lived Relief: Cortisone shots typically provide maximum relief for only 3 to 6 weeks

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Aminoglutethimide and testolactone (Teslac) were the first generation of non-selective irreversible AIs

A natural decline occurs over time in the levels of collagen, with production of new collagen decreasing and existing collagen reducing structural and functional integrity