c elegans lipid storage defective droplets and peroxisomes are co-regulated to drive lifespan extension in response to mono-unsaturated fatty acids Genome-wide RNAi analysis of Caenorhabditis
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somerae ZNN-1 enhanced muscle glucose uptake and utilization Given that glycolysis can supply both energy and carbon skeletons for protein synthesis [38], we assessed the parameters related to glucose metabolism in muscle tissue

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Results revealed a reduction in hepatic lipid accumulation and oxidative stress, hepatic fibrosis via modulation of -smooth muscle actin (SMA), peroxisome-activated receptor gamma (PPAR), and nuclear factor kappa B (Nf-B) expression (87)

LDL comprises the largest fraction of circulating lipoproteins, constituting about 60% to 70% of total cholesterol

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