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This is apparent in systems such as the circulatory system where Wnt3a leads to proliferation and expansion of hematopoietic stem cells needed for red blood cell formation

Razavi, B., et al
Interleukin-2 (IL-2) is a well-characterized cytokine that plays a key role in immune defense by stimulating regulatory T cells 49

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DNA methylation 101: What is important to know about DNA methylation and its role in SLE risk and disease heterogeneity

This was followed by human trials to confirm its impact on intracellular glutathione
