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These include reduced expression of cereblon, or other proteins involved in the UPS, genetic alterations including mutations, deletions or alternative splice variants, and upregulation of drug efflux pump(s)

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Bryant and his team explain the reasons for the benefits of IV supplementation over oral supplements

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For human organisms, there is also an internal exposure due to inhalation (mainly radon) and ingestion of naturally occurring radionuclides (K-40 and others) that adds to the mentioned external exposure, so that the total average annual dose is evaluated to be 2.4 mSv [271]

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J Physiol Paris 91(35):113122 Keremi B, Lohinai Z, Komora P, Duhaj S, Borsi K, Jobbagy-Ovari G et al (2009) Anti-inflammatory effect of BPC 157 on experimental periodontitis in rats

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Numerous studies suggest it has anticoagulant and antiplatelet properties

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2c, d) 14

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