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Around the same time, researchers began noting that decades of declining whole-fat dairy intake mirror a steady drop in C15:0 levels in the populationa trend tied to what researchers call rising cellular fragility, The molecule appears to strengthen cell membranes, strengthen mitochondria, and reduce inflammatory wear and tear

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This redundancy explains why individuals with variants in the gene encoding GLUT2 (SLC2A2 mutations, or FanconiBickel syndrome) do not have significant abnormalities in insulin secretion (89)

If glucose is available in excess, aldose reductase convert glucose into sorbitol through the polyol pathway [188]