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Drp1 siRNA and small molecule inhibitors of Drp1 prevented mitochondrial fission, loss of mitochondrial membrane potential, and cell death in glutamate toxicity or OGD in vitro , and after ischemic brain damage in vivo [57]

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[DOI] [PubMed] [Google Scholar] 21.Wu J, Cai H, Lei Z, et al

J Physiol Paris

These short siRNAs are bound to a multiproteincomplex known as RISC

Rejuvenate from Within
