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Prostate cancer cells co-cultured with adipocytes increase expression of IL1- to stimulate adipocyte lipolysis in a vicious positive feedback loop that decreases prostate cancer cell sensitivity to docetaxel and upregulates prostaglandin E2 (PGE2) synthesis in adipocytes, a prostate cancer pro-survival signal (212)

Study Billon 2023 chronic Duration 28 days Dose & Route 50 mg/kg IP twice daily Outcome (Mouse) Raised oxidative muscle fibers and OXPHOS proteins

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The targeted nanocarriers showed significantly higher permeability compared to the non-targeted nanoparticles both in control conditions and in the presence of cytokines

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Match each alcoholic drink with a glass of water