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An example was presented by Grant et al., [162] with romidepsin that is activated by intracellular GSH by cleavage of a disulfide bond

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doi: 10.1111/j.1755-3768.2011.02149.x

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Incapacity to deal with the overproduction of ROS during hyperoxia, ultimately leading to necrosis and apoptosis [83]

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Polyphenols also show neuroprotective properties by inhibiting amyloidbeta (A) aggregation and tau hyperphosphorylation, key features of AD (Freyssin et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Ricca C., Aillon A., Bergandi L., Alotto D., Castagnoli C., Silvagno F

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