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via oral administration or intraperitoneal injection) prior to IR injury can mitigate oxidative stress, enhance mitochondrial function, and alleviate organ IR injury [122,123]

J Plant Physiol 162:743748

In summary, future therapeutic innovations should move beyond simple immune suppression to a more integrated model that addresses oxidative stress, adaptive immunity, and innate immune amplification simultaneously

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Almost 90% of cellular GSH are in the cytosol, 10% is in the mitochondria and a small percentage is in the endoplasmic reticulum (Meredith and Reed, 1982

Direct and indirect antioxidant properties of inducers of cytoprotective proteins