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Description
Genotype and phenotype
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A mutation of V730 to methionine would alter the interaction surface to become more favorable to binding to LxxLL motifs and thereby to the recruitment of LxxLL motif-containing coactivators, such as the SRC coactivators, which are commonly associated with the AR in recurrent prostate cancer 7,170,171
Patients should consult their pharmacist or provider if dose adjustments are needed
doi: 10.1002/smrj.62
Bone et al., 1989) as well as more quantitative measures (Macey et al., 1996) to demonstrate increased tremor during withdrawal
