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Insufficient intrinsic factor production, common in older adults due to age-related absorption decline, can also lead to deficiency
doi: 10.6133/apjcn.2016.25.1.04
Storage: Store between 2C and 8C
This rapid increase has been argued to be due either to a release of IGF-1 stores in tissues or due to a proteolytic cleavage of IGFBP-3 either in the plasma or in tissue
