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These cytokines can promote cognitive dysfunction as they are able to disrupt the blood-brain barrier (BBB), allowing proinflammatory cytokines (355) to translocate into the brain and promote inflammation ( Figure 10 )

[DOI] [PubMed] [Google Scholar] 20.A comprehensive review of ashwagandha: therapeutic potentials and cultivation enhancement through Vrikshayurveda-based Kunapjala

One of the problems with weight loss is that everyone responds differently

[PubMed] [Google Scholar] 137.Rossignol D.A., Rossignol L.W., Smith S., Schneider C., Logerquist S., Usman A., Neubrander J., Madren E.M., Hintz G., Grushkin B., Mumper E.A

doi: 10.3389/fnagi.2021.650103 90 LuY.WangR.DongY.TuckerD.ZhaoN.AhmedM
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Therefore, the findings are expected to be broadly relevant to both male and female physiology, although future studies will be required to directly assess sex-specific effects
