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These combinations should be approached with caution, as the interactions between multiple TrkB-modulating compounds have not been systematically studied in clinical settings

Neither compound is approved by the U.S

Compared with free DOX, the MND formulation and its combination with ART in the hydrogel form significantly increased the proportion of apoptotic cells, with MND-ART-GEL treatment resulting in the highest apoptosis rate and caspase-3 activation (Fig

MUC1-C: Mucin 1 C-terminal subunit

Moreover, the release of cytochrome c (Cyt-C) from mitochondria further validated the effectiveness of the synergistic effect