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The hydrogel, when covering wound surfaces, is susceptible to damage from skin movement, which could impede wound healing and increase infection risk

Strenuous activity should be avoided for one to two weeks

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however, the large number of classes of therapies available has also introduced uncertainties in how to select and apply therapy

Role of Vitamin B12 in the Body Vitamin B12 is a water-soluble vitamin belonging to the B vitamin group and plays several important roles in the body, including: DNA Synthesis: It is involved in the synthesis of DNA, making it crucial for cell division and reproduction

Moreover, due to its multi-mechanistic pharmacological profile, it is an interesting drug to treat severe chronic pain often characterized by hyperalgesic states (e.g., cancer pain) and in opioid rotation protocols in patients experiencing inadequate pain relief or unbearable side effects with other opioids [2, 80,81,82]