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By targeting two hormone receptors, Zepbound curbs hunger and nausea
MOTS-c prevents diet-induced obesity and insulin resistance by improving glucose utilization and maintaining adipose homeostasis [5]

The compound is best known as an inhibitor of nicotinamide Nmethyltransferase (NNMT), an enzyme implicated in adipose tissue energy handling and nicotinamide adenine dinucleotide (NAD+) turnover.
