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To the best of our knowledge, this is the first combined folic acid intervention and structured teaching test, and, overall, significant improvement was noted in all subtests of the ATEC and most subtests of PEP-3 (except characteristic motor behavior, problem behavior, and personal self-care) during the three months of structured teaching

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More recently, it has become apparent that SFN can behave hormetically [137] with different effects responsive to different doses

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For instance, viral-mediated overexpression of BDNF in the PFC protects from stress-induced synaptic deficiencies by sustaining dendritic spine density and cognitive flexibility [267]

Iron (Fe 2+ ) is transported through ferroportin 1 from the luminal membrane of endothelial cells of the BBB to the abluminal membrane (Baumann et al