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Therefore, understanding how NaB influence cellular processes in the female reproductive system could unveil new therapeutic avenues for conditions such as endometriosis, PCOS, and gynecological cancers

The presence of two significant elements in the regulatory region of the MT-1 and MT-2 genes, namely, the TATA box (serving as the core promoter element) and multiple cis-acting response elements, including metal-responsive elements (MREs) and antioxidant-responsive elements (AREs), drives their expression [32]

Moreover, heavy metals could be a critical factor that triggers PCS phosphorylation [56, 69]

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Production and utilization of hydrogen peroxide associated with melanogenesis and tyrosinase-mediated oxidations of DOPA and dopamine

This might not be the only redox switch for this protein since four other cysteine residues are well conserved in APKs from terrestrial plants
