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It is produced in higher concentrations by endothelial cells and is involved in the regulation of vascular tone

In studies in mice, TMAO has been shown to cause atherosclerosis, the disease process that leads to cholesterol-clogged arteries

Short- and medium-chain fatty acids (i.e., those with a chain of up to 8 carbon molecules) do so easily, but long and very long-chain fatty acids need a transport mechanism to get through [1,4]

In addition, it summarized the effective doses and ideal timing of their intake according to analyzed studies