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A better understanding of how the ECM regulates organ structure and function and of how ECM remodelling affects disease progression will contribute to the development of new therapeutics

And in this context, the FOXO4-DRI peptide stands out as one of the most innovative molecules

Front Neuroanat 7:3 Wang B, Chang M, Zhang R, Wo J, Wu B, Zhang H, Zhou Z, Li Z, Zhang F, Zhong C et al (2022) Spinal cord injury target-immunotherapy with TNF-alpha autoregulated and feedback-controlled human umbilical cord mesenchymal stem cell derived exosomes remodelled by CRISPR/Cas9 plasmid

Over the past decade, the market has expanded into clinical applications, including wound healing and tissue engineering, driven by scientific validation and regulatory approvals in certain jurisdictions

Nordihydroguaiaretic acid (NDGA) exhibits proven senomorphic properties, extending life by 810% in male mice [129]

J Biomol Struct Dyn 39(11):40894099 Hu T, Lu XY, Shi JJ, Liu XQ, Chen QB, Wang Q et al (2020) Quercetin protects against diabetic encephalopathy via SIRT1/NLRP3 pathway in db/db mice
