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10.1016/j.neuropharm.2017.08.007 150

(PubMed) Wu Y, Zhang L, Li S, Zhang D

Refrigeration at the recommended 2C to 8C (36F to 46F) dramatically slows down this degradation process

Regular follow-up with a clinician, including testing for kidney function, and discontinuation of the drug if signs of toxicity develop are advised (Curiel 2013)

For the uterine environment to be receptive to pregnancy, there must be activation, differentiation, and expansion of toleragenic dendritic cells (tDCs) and CD4 + CD25 + Treg cells (90, 91) Evidence from a CBAxDBA/2 mouse model of pregnancy failure suggests that components of seminal fluid prime the immunological landscape of the uterine environment for implantation (92)

3.2 Cellular and molecular effects IF enhances autophagy, an essential cellular mechanism that eliminates damaged components and maintains cellular homeostasis [24]