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This approach was chosen for its ability to stabilize variance across different abundance levels

The thiol is deprotonated first, before reacting with H 2 O 2 , with the rate-determining transition state of the reaction being methanethiolate attack on H 2 O 2

Hercynylcysteine sulfide can also be synthesized from an L-histidine derivative with an N -benzyl-protected imidazole in good yield, followed by a non-enzymatic reaction with pyridoxal phosphate to yield EGT (Khonde and Jardine 2015

Activation and regulation of ATM kinase activity in response to DNA double-strand breaks

Kania, A

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