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Freezing and thawing cycles can damage peptide structures and lead to aggregation, reducing efficacy

Store at 20 C, protected from light and moisture

To prevent trauma to your penile tissue, always change sides of your penis each time you inject the medication (right side, then left side)

2021;10 doi: 10.7554/eLife.58591

The SURMOUNT-4 trial assessed the weight maintenance with tirzepatide and had also two periods: a 36-week open-label lead-in period during which all participants took tirzepatide, followed by a 52-week double-blind treatment period during which participants were randomised to either continue on tirzepatide or switch to placebo