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Some researchers prefer adding 2.5 mL for a 4 mg/mL concentration, especially when they need finer dose adjustments during dose titration phases

A randomized controlled trial of single doses of morphine, lorazepam and placebo in healthy subjects

Note, portal hypertension, along with caval and intracranial hypertension and aortal hypotension, was regularly eliminated/attenuated [129,130,131,132,133,134,135,136,137,138,139,140,141,142]

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