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6 System is a cystine/glutamate antiporter that facilitates the exchange of cystine and glutamate across the plasma membrane

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demonstrated changes in various metabolites, including elevated levels of citrate, cis-aconitate, GDP, and sedoheptulose-7-P, alongside decreased levels of glutamate, -ketoglutarate, succinate, fumarate, malate, and C5-Carnitine