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Conditions like seborrheic dermatitis and folliculitis create inflammatory environments hostile to healthy hair

During an immune/inflammatory response a combination of enhanced utilization of cysteine for GSH synthesis and cell replication may be what leadsto a depletion of cellular SAM

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Cell 82 , 22982314 (2022)

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In conclusion, the persistent presence of UPEC in bladder epithelial cells involves ferritinophagy, which promotes bladder epithelial cell death, exacerbating the severity of urinary tract infections
