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Endotoxemia is also believed to participate in the pathogenesis of many liver diseases including alcoholic liver disease and non-alcoholic steatohepatitis (Su, 2002

To this extent, previous reports have shown that the control of MZB localization in the spleen depends on signals delivered by integrins and chemokines such as ICAM-1 and VCAM-1 16,53

serum and plasma [5760], synovial and uterine fluids [59, 61], intestinal Paneth cells [62, 63] and granulocytes [31] (Figure 1)

Furthermore, crocin induced NF-B translocation from the nucleus to the cytoplasm ( Figure 6A ), and the expression of NOS2, IL-33 was inhibited by crocin ( Figures 6D, E )

Information from Ehlers Danlos Society.

J.MirnicsK.LevittP.et al (2007)