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Microvasc Res 23: 380384

coli , having higher relative abundance in PV patients
& Prakash, C

In mice, a high-fat diet has also been shown to impair leptin signaling by attenuating STAT3 activation, thus contributing to leptin resistance [18].Leptin receptor activation engages intracellular proteins, such as protein tyrosine phosphatase1 B (PTP1B) and suppressor of cytokine signaling-3, that terminate receptor signaling

Overall process variability was checked by calculating the median RSD for all endogenous metabolites (i.e., non-instrument standards) present in 100% of the pooled matrix samples (see the median RSD values for instrument variability and process variability in Supplementary Table 3)

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