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Therefore, promoting the apoptosis of senescent endothelial cells and improving the microenvironment of aged blood vessels is crucial for maintaining vascular function

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32 This is due to metabolic reprogramming in the BM niche, which shifts from oxidative phosphorylation to aerobic glycolysis reducing ATP and simultaneously increasing NAD +

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Zhang X, Yang F, Han L, Su Q, Gao Y, Wu R, et al

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