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This Notch intracellular domain (NICD) relocates to the nucleus, where it forms a tertiary complex with CSL (CBF1/Suppressor of Hairless/LAG-1) transcription factors and Mastermind-like protein (MAML-1), leading to the activation of Notch target genes

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The insulinogenic index was more significantly improved in the SR group

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The key message is simple: if something does not seem normal or recovery is not progressing as expected, it is always better to ask your clinic

Regulation of NT-PGC-1alpha subcellular localization and function by protein kinase A-dependent modulation of nuclear export by CRM1