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Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis

It is notable that the beneficial effect of ARA 290 appears to be sustained for at least the 28-d follow-up period

Magalhaes E, Magalhaes S, Brown B, Qiu Y, Kornblau SM

All samples were analyzed in triplicate, and the 16 S rRNA gene was used as an endogenous control, as described in our previous publication

Updated 6/2/25

CaM-KII is a sophisticated enzyme involved in synaptic plasticity, performing key roles in both long-term potentiation (LTP) and long-term depression (LTD) (for a review, see Bayer & Giese, 2025)