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4 The bodys metabolic rate increases during high-intensity exercise, increasing the demand for oxygen to produce muscle energy

About this article Cite this article Zhou, C., Zhang, S., Li, Y

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In fact, nuclear exclusion of BACH1 has been reported to be necessary for the activation of neuroprotective pathways through its antioxidant target gene: HMOX-1, the rate-limiting enzyme in heme catabolism (Reichard et al., 2007)

SIRT3 also regulates mitochondrial dynamics and biogenesis in response to oxidative stress via the forkhead transcription factor FOXO3 [319]

33 Oxidative stress is associated with the pathophysiology of cardiovascular diseases (CVDs), while antioxidants are involved in neutralizing ROS and protecting against oxidative stress