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Treatment of military acoustic accidents with N-Acetyl-L-cysteine (NAC)
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S2J+K) and FOXO4 knockout mice do not show a striking phenotype (Hosaka et al., 2004

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Vlavcheski F, Baron D, Vlachogiannis IA, MacPherson RE, Tsiani E (2018) Carnosol increases skeletal muscle cell glucose uptake via AMPK-dependent GLUT4 glucose transporter translocation

Further complicating the matter, in brewing yeast there exists more complete and less complete versions of the IRC7 gene (long and short versions), differing levels of intact promoter regions (which effectively turn on the gene), and differing allelic profiles (how the gene is carried on different chromosomes) all of these things affect the level of activity of this -lyase enzyme
