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reported that Sym004 could induce a significant reduction in c-MET, Akt, and MAPK phosphorylation in cetuximab-resistant CRC cancer cells (GEO-CR and SW48-CR) even in the presence of the high-affinity ligand TGF (Napolitano et al., 2017a)

Abstract: Pastore, A., Federici, G., Bertini, E., & Piemonte, F

Since the synthesis and expression of GPx4 are regulated by various cellular processes, targeting GPx4 may constitute a promising strategy for the induction of ferroptosis and the promotion of cancer cell death in treatment-resistant cancers (Lee and Roh 2023)

Des preuves convaincantes montrent que la synthse de GSH est rgule principalement par lactivit de la gamma-glutamylcystine synthtase, la disponibilit de la cystine et linhibition de la rtroaction de GSH

A review of implantable biosensors for closed-loop glucose control and other drug delivery applications

In a survey, 73% of cancer patients reported using herbal supplements within the past 30 days