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doi: 10.1016/j.ygyno.2004.10.012

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Nonetheless, in organotypic hippocampal cultures with preserved neuronal-glial interactions roxadustat decreased the neuronal susceptibility to ischemic stress, which was largely prevented by restricting glycolytic energy production through lactate transport blockade

doi: 10.1158/2159-8290.CD-19-1384 47 MallaRRVasudevarajuPVempatiRKRakshmithaMMerchantNNagarajuGP

Zimmer et al., 2000) and acts as a metabolizing enzyme by increasing the uptake and absorption of vitamin E and hence facilitates an anti-proliferative effect most notably in prostate cancer and as a tumor suppressor in cancer through a non-vitamin E mechanism