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Alpha-Lipoic Acid: Molecular Mechanisms and Therapeutic Potential in Diabetes

Such levels are difficult to interpret because they can also occur in association with megaloblastic anemia produced by folate deficiency and in iron deficiency (Amos et al., 1994

The lack of vitamin B12 may result from any of the following conditions: Addisonian (pernicious) anemia this condition causes autoantibody formation against parietal cells, which results in a lack of IF essential for absorption of vitamin B12 from the intestine Malabsorption impaired absorption of vitamin B12 Gastrointestinal pathology, dysfunction, or surgery these include atrophic gastritis, celiac disease, small bowel bacterial overgrowth, pancreatic insufficiency, Helicobacter pylori infection, gastric carcinoma, and total or partial gastrectomy Diphyllobothrium latum and related species (the fish tapeworm) infestation these parasites compete with vitamin B12 for intestinal absorption

The supplement formulation is suitable for daily use and enhances the efficacy of glutathione therapy

Several independent investigations have shown that zinc deficiency, which can also be triggered by various diseases, is associated with a compromised barrier function [81]

Recently, it was proposed that the aforementioned drug V-9302 targets SLC38A2 and SLC7A5 rather than SLC1A5 87