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Handling best practices Minimize the time reconstituted vials spend out of refrigeration Never touch the rubber stopper with anything except an alcohol-swabbed needle Draw doses quickly and return vial to refrigerator immediately Use a fresh needle for each vial entry to minimize contamination risk Never share vials between users Contamination is a significant risk with multi-dose vials

Mild vitamin B12 deficiency can be treated with dietary changes or by taking vitamin B12 supplements

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doi:10.1038/newbio243085a0

Preclinical safety evaluations revealed no toxicity in acute studies with SD rats and beagles following intravenous/intramuscular administration [10]

Processing of X-ray diffraction data collected in oscillation mode